Perivascular mesenchymal stem cells in the adult human brain: a future target for neuroregeneration?
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Perivascular mesenchymal stem cells in the adult human brain: a future target for neuroregeneration?
Perivascular adult stem cells have been isolated from several tissues, including the adult human brain. They have unique signatures resembling both pericytes and mesenchymal stem cells. Understanding the nature of these cells in their specific vascular niches is important to determine their clinical potential as a new adult stem cell source. Indeed, they have promising features in vitro in term...
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Blood vessels and adjacent cells form perivascular stem cell niches in adult tissues. In this perivascular niche, a stem cell with mesenchymal characteristics was recently identified in some adult somatic tissues. These cells are pericytes that line the microvasculature, express mesenchymal markers and differentiate into mesodermal lineages but might even have the capacity to generate tissue-sp...
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ژورنال
عنوان ژورنال: Clinical and Translational Medicine
سال: 2012
ISSN: 2001-1326,2001-1326
DOI: 10.1186/2001-1326-1-30